文章摘要
伏邪理论与BRCA1/2基因突变:一个中西医结合视角下的卵巢癌发病机制探析
Incubated Pathogenic Theory and BRCA1/2 Mutations: Discussion on the Pathogenesis of Ovarian Cancer from Perspective of Integrated Traditional Chinese Medicine(TCM) and Western Medicine(WM)
投稿时间:2018-01-06  录用日期:2018-01-15
DOI:
中文关键词: 卵巢癌  伏邪  先天伏寒证  伏毒  BRCA1/2基因突变
英文关键词: ovarian cancer  Incubated Pathogenic Theory  congenital latent cold syndrome  latent toxicity  BRCA1/2 mutations
基金项目:国家自然科学基金项目(No.81473717)
作者单位邮编
肖乔 黑龙江中医药大学 150040
沈影 黑龙江中医药大学 150040
韩凤娟* 黑龙江中医药大学附属第一医院妇科一科 150040
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中文摘要:
      伏邪理论自《黄帝内经》发展至今,仍为中医学病因理论的重要部分,为恶性肿瘤、冠心病、过敏性疾病等疑难杂症提供治疗思路。卵巢癌在妇科肿瘤中恶性度最高,早期难以发觉,治疗难度大。文章以伏邪理论探讨卵巢癌,认为卵巢癌根源在于先天伏寒体质,以伏毒入络为病理因素,与西医遗传因素中BRCA1/2基因突变的影响具有相关性。通过探讨卵巢癌病因中伏邪理论与BRCA1/2基因突变是否具有一致性,进而为中医学预防及改善卵巢癌状态提供思路。
英文摘要:
      Incubated pathogenic theory, which derives from Yellow Emperor’s Inner Canon ,is a significant part of etiology theory from TCM. This theory provides treating ideas for incurable diseases, such as malignant neoplasms, immune system diseases. Ovarian cancer is the most lethal gynecological tumors for its difficult to early detect and treatment. provides treatment ideas for incurable diseases such as malignant tumors, coronary artery disease and allergic diseases. Ovarian cancer has the highest malignant degree in gynecologic tumors. The article explores ovarian cancer’ etiology with incubated pathogenic theory, and believes that the origin cause of ovarian cancer is congenital latent cold syndrome and latent toxicity factor.By exploring the etiology of ovarian cancer with incubated pathogenic theory and BRCA1/2 mutations , thus provide ideas for the prevention and improvement of ovarian cancer in traditional Chinese medicine.
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